An Integrated Method for Detecting Micro RNA Target Proteins through Reverse-phase Protein Arrays

Monitoring Proteins and Protein Networks Using Reverse Phase Protein Arrays

Recent advances in high throughput, high content "omic" technologies coupled with clinical information has lead to the expectation that the complexity of the molecular information generated will lead to more robust scientific research as well as the expectation that overarching therapeutic approaches will be patient-tailored to the underlying specific molecular defects of the disease. As diseas...

An Integrated Approach for Collection Center Selection in Reverse Logistics

In this paper, a hybrid multi-criteria decision-making (MCDM)-method and mixed integer linear programming (MILP) approach in order to evaluation of the returned products' collectors along with their ordered quantities, is utilized. Firstly, the most important criteria of collection center in the car industry are identified. Then, in order to evaluate these proposed criteria, a hybrid Fuzzy Deci...

Variable slope normalization of reverse phase protein arrays

MOTIVATION Reverse phase protein arrays (RPPA) measure the relative expression levels of a protein in many samples simultaneously. A set of identically spotted arrays can be used to measure the levels of more than one protein. Protein expression within each sample on an array is estimated by borrowing strength across all the samples, but using only within array information. When comparing acros...

Development of Optical Imaging Method for Detecting Rna-protein Interactions

A micro method for detecting indol formation.

The acid in the commonly used indol reagent described by Kovacs (1928, 1932) and Diagnostic Procedures and Reagents (1950) changes the reaction of the medium in which the indol production is tested and prevents the further observation of biochemical processes, killing the bacteria themselves. It was found that, by heating 0.1 ml. or less of culture (broth or peptone water), indol production by ...